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Personalizing Beta-Blocker Therapy
The recently published article by Duarte et al. provides comprehensive guidelines on how genetic variations influence the pharmacokinetics and pharmacodynamics of beta-blockers. Below is a […]
CYP450 Enzymes: Masters of Metabolism and Disease
A review of CYP450 enzymes.
Genetic Polymorphisms and Anti-Seizure Medications
In a compelling overview, D’Onofrio and colleagues summarized what is known about pharmacogenetic interactions of anti-seizure medication. Here is the summary of their paper. Introduction What […]
The Impact of PGx Testing for Cytarabine in AML
In this paper, Lamba and colleagues investigated the possible reasons for outcome disparities between different ethnicities treated with similar regimens for AML. Key Findings 1. […]
Mastering PGx Tests: The ABCD Guide
In the rapidly evolving field of pharmacogenomics, the integration of genetic testing into patient care can seem daunting. To demystify this process and enhance clinical […]
The Urgent Need for Inclusive Pharmacogenetic Panels
An interesting brief communication by Kennedy and colleagues appeared in the Genomic Medicine journal from Nature in February 2024. Study starting points The study evaluated […]
The Genetic Puzzle Behind Tamoxifen Response: Beyond CYP2D6?
Tamoxifen remains a cornerstone in the treatment of breast cancer, yet patient outcomes vary greatly. This variability may stem from genetic differences in how tamoxifen […]
Bridging Genes and Algorithms: The Pathway to Precision Medicine Through Machine Learning and Pharmacogenomics
The following is a concise summary of an excellent extensive article by Mondello and colleagues, which delves into the intricate intersection of Machine Learning and […]
Pharmacogenomic Testing for Cancer Patients: Breaking the Barriers!
challenges hindering equitable pharmacogenomic (PGx) testing and implementation in oncology.
A New Era in Mental Health: Pioneering Study about Pharmacogenomics in Psychiatry
I was profoundly impressed by the groundbreaking research in the recent journal article “Clinical Implementation of Preemptive Pharmacogenomics in Psychiatry” The depth of the research, […]
Evaluating the Impact of Pharmacogenomic Tools on Depression Treatment: Separating Evidence from Expectation
In their thorough meta-analysis, Milosavljević and colleagues critically evaluated the evidence supporting the effectiveness of current pharmacogenetic tools in enhancing treatment outcomes for depression. Their […]
